研究方向：情绪和学习记忆的神经机制研究和临床应用
电子邮箱：xiaoxiao@fudan.edu.cn
个人网站：https://faculty.fudan.edu.cn/xxiao/zh_CN/index.htm
简要介绍：
复旦大学类脑智能科学与技术研究院青年研究员，博士生导师。复旦大学认知神经科学中心执行主任。上海市青年科技启明星，上海市民建科教委员会副主任，上海民建人工智能专委会副主任，上海市神经科学学会疼痛转化研究分会委员，中国生理学会青年委员会委员。
研究专长为使用认知心理学、分子基因工程改造、脑电生理结合双光子成像和计算神经科学等交叉学科手段，对情感障碍和认知缺陷的神经环路和分子机制进行深入探究，并为脑内超微环路中单突触可塑性的记录建立新型实验方法，取得了一系列重要成果，在神经生物学权威期刊：Cell Reports（3篇），Journal of Neuroscience（2篇），Neuroscience Biobehavioral Reviews，Cerebral Cortex，Pain，Anesthesiology等共发表论文20余篇，其中以第一或通讯作者（含共同）14篇。其中，围绕“疼痛的中枢机制及可塑性调控”这一科学主题，系统研究了神经可塑性调控的分子机制、疼痛信息处理的中枢机制、以及疼痛可塑性调控，推动了疼痛神经机制研究的发展。
研究成果被领域内顶尖期刊多次正面引用，包括Science，Nature等，并被临床神经病学教科书Handbook of Clinical Neurology和神经病理性疼痛测量教科书The Oxford Handbook of the Neurobiology of Pain引用与收录；申请发明专利4项（获批2项），实用新型专利2项（获批2项）。与杨雄里院士合著中文科普著作《探索脑的奥秘》，翻译英文译著2本，其中神经外科医生Oliver Sacks著作《最初的爱，最后的故事》，获豆瓣网“科学·新知”年度榜单Top10推荐。
代表成果：
1. Serpin family proteins as potential biomarkers and therapeutic drugs in stroke: A systematic review and meta-­analysis on clinical/preclinical studies. Bing Yan, Lu Luo, Li Liu, Zhenyu Wang, Ruiying Chen, Yi Wu,Xiao Xiao#,CNS Neuroscience & Therapeutics, (2023) 00:1–12.
2. Design and evaluation of a rodent-specific focal transcranial magnetic stimulation coil with the custom shielding application in rats. Li Liu, Ming Ding, Junfa Wu, Yuwen Zhang, Shaoqian Guo, Nianhong Wang, Kewei Yu, Lu Luo, Qianfeng Wang, Yuanfeng Weng, Quan Zhang, Kai Qiu, Yi Wu#,Xiao Xiao#, Qun Zhang#,Frontiers in Neuroscience, (2023) DOI: 10.3389/fnins.2023.1129590
3. 广义线性模型在神经电生理信号分析中的应用。刘子悦;肖晓#，复旦学报（自然科学版）, (2023), DOI:10.15943/j.cnki.fdxb-jns.20230318.001
4. A tassel-type multilayer flexible neural probe prepared by laser direct writing. Zipeng Ye, Jing Qi, Yiling Ni, Zhiyong Wu,Xiao Xiao#, Shisheng Xiong#,Chip, (2022). 1 (3), 100024. DOI: 10.1016/j.chip.2022.100024(Cover paper)
5. Corticospinal circuit neuroplasticity may involve silent synapses: implications for functional recovery facilitated by neuromodulation after spinal cord injury. Mingcong Chen, Zuxin Chen,Xiao Xiao, Libing Zhou, Rao Fu, Xian Jiang, Mao Pang, Jianxun Xia#,IBRO Neuroscience Reports(2022). 14, 185-194
6. The role of glia underlying acupuncture analgesia in animal pain models, a systematic review and meta-analysis. Bing Yan, Shengyu Tang, Yuqiu Zhang,Xiao Xiao#,Pain Medicine(2022)., 24 (1), 11-24; doi: 10.1093/pm/pnac115
7. 影响老年人认知健康的街区环境要素——基于2000—2021年国际研究进展。袁琦;陈泳#;肖晓,新建筑,2022, (03): 146-150.
8. Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice. Lu Luo*, Meixi Liu*, Yunhui Fan, Jingjun Zhang, Li Liu, Yun Li, Qiqi Zhang, Hongyu Xie, Congyu Jiang, Junfa Wu,Xiao Xiao#, Yi Wu#,Journal of Neuroinflammation(2022) 19:141
9. Neurophysiological characteristics in the periventricular/periaqueductal graycorrelate withpain perception, sensation, and affect in neuropathic pain patients. Huichun Luo*, Yongzhi Huang*, Alexander L. Green, Tipu Z. Aziz,Xiao Xiao, Shouyan Wang#,NeuroImage: Clinical(2021).32, 102876
10. MonkeyPosekit: Automated Markerless 2D Pose Estimation of Monkey, Chuxi Li, Chi Yang, Yerong Li, Shufei Feng, Zhen Zhang, Shisheng Xiong#,Xiao Xiao#,IEEE- China Automation Congress (CAC)(2021) 1280-1284
11. 基于时移和片组注意力融合的双流行为识别网络.肖子凡,刘逸群,李楚溪,张力,王守岩,肖晓#计算机系统应用Computer Systems & Applications, (2022) 31(1):204−211
12. The role of the anterior cingulate cortex in translational pain research.Xiao Xiao#,Ming Ding, Yuqiu Zhang#,Neuroscience Bulletin(2021) 37(3), 405-422
13. Distinct function of estrogen receptors in the rodent anterior cingulate cortex in pain-related aversion. Kai-Kai Zang *,Xiao Xiao*,Li-Qiang Chen,Yan Yang, Qi-Lai Cao, Yu-Long Tang, Su-Su Lv, Hong Cao, Ling Zhang, Yu-Qiu Zhang.Anesthesiology(2020) Jul;133(1):165-184;
14. Functional dynamics of thalamic local field potentials correlated with modulation of neuropathic pain. Huichun Luo, Yongzhi Huang,Xiao Xiao, Wenjing Dai, Yingnan Nie, Xinyi Geng, Yongzhi Huang, Alex Green, Tipu Aziz, Shouyan Wang#,European Journal of Neuroscience. (2020) 51:628–640
15. Trio haploinsufficiency causes neurodevelopmental disease-associated deficits. Sara M. Katrancha, Amy Zhao, Amanda Jeng, Juliana Shaw, Minsheng Zhu, Christopher Pittenger, Charles Greer,Xiao Xiao#, Anthony J. Koleske#Cell Reports.(2019) 26:2805-2817
16. A new perspective on the anterior cingulate cortex and affective pain.Xiao Xiao, Yuqiu Zhang*.Neuroscience & Biobehavioral Reviews(2018) 90:200-211
17. Noonan syndrome-associated SHP2 dephosphorylates GluN2B to regulate NMDA receptor function. Aaron D. Levy*,Xiao Xiao*,Suma Priya Sudarsana Devi, Anton M. Bennett, Charles A. Greer, James R. Howe, Kazuya Machida, Anthony J. Koleske#Cell Reports(2018) 24 (6):1523-1535
18. CNS neurons deposit Laminin α5 to stabilize synapses. Mitchell H. Omar,Maghan Kerrisk Campbell,Xiao Xiao, Qiaonan Zhong, William J. Brunken, Jeffrey H. Miner, Charles A. Greer, Anthony J. Koleske#,Cell Reports(2017) 21(5): 1281-1292
19. Disruption of coordinated presynaptic and postsynaptic maturation underlies the defects in hippocampal synapse stability and plasticity in Abl2/Arg-deficient mice.Xiao Xiao,Aaron D. Levy, Brian J. Rosenberg, Michael J. Higley, Anthony J. Koleske#,Journal of Neuroscience, (2016) 36 (25): 6778-6791
20. SIP 30 Is Required for Neuropathic Pain-Evoked Aversion in Rats. Mei Han,Xiao Xiao, Yan Yang, Ru-Yi Huang, Hong Cao, Zhi-Qi Zhao, Yu-Qiu Zhang#,Journal of Neuroscience,(2014) 34(2): 346-355
21. Estrogen in the anterior cingulate cortex contributes to pain-related aversion.Xiao Xiao, Yan Zhang, Yan Yang, Zhi-Qi Zhao, Yu-Qiu Zhang#,Cerebral Cortex (2012) 23(9): 2190-2203
22. Estrogen facilitates spinal cord synaptic transmission via mambrane-bound estrogen receptors: implications for pain hypersensitivity. Yan Zhang,Xiao Xiao, Zhi-Qi Zhao, Yu-Qiu Zhang#,Journal of Biological Chemistry,(2012) 287(40):33268-81
23.综述：一念放下，万般自在——我们能否训练自己去遗忘疼痛.肖晓,生理学报Acta Physiologica Sinica, June 25, 2011, 63(3): 293–295
24. NMDA NR2A and NR2B receptors in the rostral anterior cingulate cortex contribute to pain-related aversion in male rats. Ting-Ting Li*, Wen-Hua Ren*,Xiao Xiao*, Long-Zhen Cheng, Xue-Han Zhang, Zhi-Qi Zhao, Yu-Qiu Zhang#.Pain,(2009) 146, 183–193
